Healthier Cells.
Better Therapies.
Industry-First Negative Selection at Scale
The AlerionTM Microbubble Cell Separation System leverages microbubble technology via negative selection, positive selection, and cell depletion workflows to enable better therapies via isolation of healthier cells. Faster. Gentler. Meaningful outcomes.
As Featured In
The Alerion™ Microbubble
Cell Separation System
Who is using Alerion™
Akadeum’s microbubble technology improves production and engineering efficiency of therapeutic CAR-T cells in a scalable manner.
Everything cell therapy scientists are looking for in cell separation technology.
Superior Cell Health
High Viability
Improved Recovery
Increased Scalability
Gentle
Faster
How it Works
Three simple stages of buoyant separation
1. Microbubbles mix with the sample.
2. Microbubbles capture target cells.
3. Target cells float to the surface for removal.
What Our Customers Are Saying
With the microbubble leukopak isolation kits, we have been able to isolate more cells in a way that’s faster and easier than ever before. ZenBio (a BioIVT company) prides itself on providing the best quality products and solutions for our research partners and tools like Akadeum’s microbubble isolation kits help us deliver on our mission.
Will Plentl, Chief Operating Officer
ZenBio Inc. (a BioIVT Company)
We found the system easy to operate and were even able to process multiple donors on the Alerion™ simultaneously during our runs, allowing us to increase our experimental throughput, which was an additional benefit.
Julian Kopelove, Senior Process Development Associate
Poseida Therapeutics
At Comprehensive Cell Solutions, we are dedicated to streamlining our manufacturing processes, reducing turnaround times, and producing safer, more effective products. Using the Alerion™ system, we’ve achieved remarkable improvements in cell viability, purity, and recovery, while significantly reducing impurities compared to conventional magnetic separation methods. This improvement led to a higher quality intermediate which we expect would result in superior product quality downstream. Our team found Alerion™ easy to use and effective at speeding up process times.
Rubina Pal, Ph.D., Sr Director, Process & Analytical Development
Comprehensive Cell Solutions
More Than Microbubbles
We’re tackling the bigger questions through partnerships
At the heart of it, our microbubbles offer a simple and elegant solution to a nearly infinite range of applications and industries. We are actively seeking partner relationships to find new and innovative ways to functionalize our technology to solve big problems. As industry needs have evolved over the last decades, existing technology has essentially remained unchanged – which is where our platform technology comes in. Whatever challenges you may be facing, from scaling up diagnostic capabilities to rare cell and environmental applications, we’re here to help.
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