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Updated on Dec 10, 2024 Share

Isolating Cell Cultures From a Medium The process of culturing cells involves the introduction of a host population to a growth medium, allowing the population to reproduce quickly in a nutrient-rich environment. After enough cells have spawned to satisfy the requirements of the intended experiment, those same cells need to be removed from the cell culture medium. The cells are intertwined within the substance in which they multiplied and need …

Updated on Dec 9, 2024 Share

Contamination in Cell Cultures Medical research is an ever-evolving field that continues to contribute to the advancement of human health. A key component of this type of research is the process of cell culturing, which involves the isolation and expansion of a cell population. The cell culture process begins with the extraction of a target sample. Once the desired cells have been acquired, they must be purified to minimize contamination. …

Updated on Dec 2, 2024 By Dominique Badea, PhD Share

T Cells are a critical component of the immune system. They play a pivotal role in the body’s defense against infections, cancer, and a variety of other diseases. To harness the full potential of these immune warriors, scientists have worked hard on perfecting the art of T cell culturing. Research and development of new immunotherapies requires robust techniques to purify and culture T cells. This article serves as a primer …

Updated on Dec 9, 2024 Share

T Cells and COVID-19 The body is naturally equipped with a variety of T lymphocytes that work together to fend off harmful pathogens. The human immune system routinely battles mild diseases with recognizable antigens. By attacking the source of a virus or bacteria, damage to healthy cells can be minimized. The T cell immune response to COVID-19 is different because it’s caused by an RNA virus (SARS-CoV-2). RNA viruses insert …

Updated on Dec 9, 2024 Share

RNA-Sequencing Medical advancements have provided researchers with strategies that change the way in which we understand biology. Scientists are now capable of studying coded protein patterns at a genomic level. RNA-sequencing (RNA-seq) is the process of detecting and analyzing the messenger RNA (mRNA) of a cell type. The range of mRNA molecules present in an organism is also known as the transcriptome. Identifying a biological transcriptome can give a better …

Updated on Nov 20, 2024 Share

Tumor-infiltrating lymphocyte (TIL) therapy is a modern cancer treatment used to combat notoriously hard-to-treat solid tumors. Like other adoptive cell therapies, TIL harnesses the body’s immune system to combat malignancies by using T cells, a type of white blood cell integral to immune response. Except in TIL therapy, these T cells are directly extracted from tumors. Having survived the tumor microenvironment, these lymphocytes are already primed to recognize and attack …

Updated on Dec 2, 2024 By Jason Ellis, PhD Share

Researchers and clinicians constantly adapt medical research and cancer treatment to overcome new challenges. When more traditional methods fail to fend off certain malignancies, patients can now turn to adoptive cell therapy as a new treatment option. Adoptive cell therapy involves the combination of human T cells with scientific enhancements to treat diseases the body isn’t adequately equipped to handle on its own. Introducing Next-Gen Cell Separation With Akadeum’s Microbubbles: …

Updated on Dec 10, 2024 Share

Immunotherapy Immunology is the study of the immune system and what it can do, immunotherapy is the study of how to do things the immune system can’t do. In immunotherapy, researchers observe and manipulate T cells in the body in an effort to make up for humans’ natural deficiencies. There are multiple methods of immunotherapy — each for different purposes. While some strategies merely extract T cells for a population …

Updated on Sep 27, 2024 Share

Proteins are large molecules in the body that play a critical role in virtually everything that happens. Movement, maturation, and other processes are not possible without a lot of proteins. Protein therapy is a form of treatment that involves sending in well-structured proteins to a precise target location to repair or replace damaged ones. This is one of the most widely used treatment methods due to its accuracy and lack …

Updated on Dec 9, 2024 Share

Cell Loss in Separation and Isolation Assays When performing research, it’s easy to forget that individual cells are living things. Each one has its own role and internal organelles that help it survive from day-to-day. The process of isolating cells for research and removing them from their ideal environment can be harmful. Significance With each lost cell the sample becomes less valuable. Often, the goal of isolating cells is to …