Case Studies
Get the Data: Alerion™ Case Study Overview
AlerionTMMicrobubble Cell Separation System Delivers Improved Cell Health and Viability for More Efficacious Cell Therapies
Updated on Nov 22, 2024 Share
Poseida Therapeutics, a clinical-stage allogeneic-focused therapeutic developer leveraging proprietary technologies to create life-saving cell therapies, selected the Akadeum platform, consisting of the new Alerion™ Microbubble Cell Separation System, the innovative BioRise™ consumable, and the Human T Cell Leukopak Isolation Kit, to improve workflows for its cancer and genetic disease solutions. A critical step in developing these therapies is isolating T cells from leukapheresis material. This requires an isolation process that …
Enhancing T Cell Isolation with Akadeum’s Alerion™ Microbubble Cell Separation System: A Case Study With Comprehensive Cell Solutions
Updated on Nov 22, 2024 Share
Comprehensive Cell Solutions (CCS), a business unit of the New York Blood Center Enterprises, is a Contract Development and Manufacturing Organization. CCS recently evaluated the Alerion™ Microbubble Cell Separation System, the BioRise™ consumable, and the negative selection Human T Cell Leukopak Isolation Kit. CCS is dedicated to streamlining their manufacturing process and requires a platform that is flexible, efficient, and consistently delivers high-performance results to meet the demands of cell …
Akadeum’s AlerionTMMicrobubble Cell Separation System: A Case Study in T Cell Banking
Updated on Nov 22, 2024 Share
Akadeum Life Sciences has partnered with a cell therapy AlerionTM Microbubble Cell Separation System beta customer to help their team develop an improved method for T cell banking. The company faces significant challenges in recovery, purity, and processing time with its existing manual methods, and Akadeum’s AlerionTM is well suited to overcome the challenges with its proven superior cell recovery, purity, and scalability. The Challenge To develop and deliver effective …
Enriching CD3+ T Cells with Alerion™ Microbubble Cell Separation System
Updated on Nov 22, 2024 Share
A cell therapy company sought to improve its CD3+ T cell isolation process. To address the challenges it faces with its current method for recovery, purity, and processing time, it partnered with Akadeum Life Sciences to evaluate the Alerion™ Microbubble Cell Separation System in conjunction with the BioRise™ consumable and Human T Cell Leukopak Isolation Kit. They chose to evaluate the Alerion™ Microbubble Cell Separation System due to: Better cell …
Using Akadeum’s Human CD4+ T Cell Isolation to Study Pathogenesis of Human Hepatotropic Viruses
Updated on Nov 5, 2024 Share
Use of Akadeum’s gentle and effective Human CD4+ T Cell Isolation Kit results in a highly enriched sample of human CD4+ T cells, enabling detection and isolation of low-abundance, antigen-specific CD4+ T cells in patient samples. A research group led by Professor Georg Lauer at Massachusetts General Hospital and the Harvard Medical School recently used Akadeum’s Human CD4+ T Cell Isolation Kit to obtain high purity enrichment of viable, healthy …
Using Akadeum’s Mouse B Cell Isolation Kit to Study Anti-Tumor DNA Vaccines to B Cells as an Alternative to Chemotherapy
Updated on Nov 5, 2024 Share
Use of Akadeum’s gentle Mouse B Cell Isolation kit results in a highly enriched sample of B cells that are healthy and retain their antigen-presenting capabilities. A researcher, Ichwaku Rastogi, from the Doug McNeel Lab at the University of Wisconsin, used the Mouse B Cell Isolation Kit from Akadeum Life Sciences to obtain a high purity isolation of viable, healthy B cells. The researchers are looking into targeted delivery of …
Using Akadeum’s Mouse T Cell Isolation Kit to study immunological processes of vaccine mediated immunity
Updated on Nov 5, 2024 Share
Use of Akadeum’s gentle Mouse T Cell Isolation kit results in a high purity T cell population while retaining cellular viability. Get an inside look at how Akadeum’s products perform in real-world research that is happening in laboratories across the country. A research group, led by Evan Scott at Northwestern University, used the Mouse T Cell Isolation Kit from Akadeum Life Sciences to obtain a high purity isolation of viable, …
Using Akadeum’s Mouse B Cell Isolation Kit to study B cell differentiation into plasma cells
Updated on Nov 5, 2024 Share
Akadeum’s gentle Mouse B Cell Isolation kit produces high purity B cell population without affecting physiology or differentiation potential. Get an inside look at how Akadeum’s products perform cell separation in real-world research that is happening in laboratories across the country. A research group at the University of Pennsylvania used the Mouse B Cell Isolation Kit from Akadeum Life Sciences in their research into the mechanisms that underlie the differentiation …
Using Akadeum’s Mouse B Cell Isolation Kit to study autoreactive B cell activation and differentiation
Updated on Nov 5, 2024 Share
“The resulting sample looked perfect after using microbubbles – very happy with the product.” Get an inside look into how products from Akadeum Life Sciences perform in real-world research that is happening in laboratories across the country. A research group at the University of California San Francisco recently used the Mouse B Cell Isolation Kit from Akadeum Life Sciences in the course of their research into understanding how autoreactive B …
Using Akadeum’s Mouse T Cell Isolation Kit to study the affect of dietary alterations on immune cells
Updated on Nov 5, 2024 Share
“Akadeum cell isolation kits isolate high purity samples in a matter of minutes, no magnets needed!” At Akadeum Life Sciences, we love to hear how our products perform in real-world research that is happening in laboratories across the country. A research group at a prestigious east coast laboratory recently used the Mouse T Cell Isolation Kit from Akadeum Life Sciences in the course of their research into understanding the link …